Graft vs. host disease. This occurs only in an allogeneic transplant, and the risk depends upon the tissue type match of the donor, and whether the blood stem cells are processed to remove cells that may cause GVHD. In GVHD, certain cells from the donor (T cells) may identify cells in the patient’s body (the host) as foreign. The cells are then attacked, damaging organs such as the skin, liver and intestines. To avoid this complication of a BMT, immunosuppressant drugs may be given to suppress the donor’s T cells, or the blood stem cells may be processed to remove T cells.
see Graft-versus-host disease
(graft-versus-host disease): A reaction of donated bone marrow against a patient's own tissue.
graft versus host disease. the condition that results when the immune cells of a transplant (usually of bone marrow) from a donor attack the tissues of the person receiving the transplant.
Graft-versus-host disease. A reaction of donated stem cells against the patient's tissue.
A reaction of donor cells (grafts) to the recipients cells and organs (hosts). A syndrome seen almost exclusively in the allogeneic bone marrow transplant population.
Graft versus host disease. a common, and serious, complication of bone marrow transplantation. Some of the donor's immune cells reject the patient's own cells as foreign. The skin, liver and gut may be affected.
Graft Versus Host Disease. A potential complication of transplants associated with the use of blood or tissue from a different person ( allogeneic). In GVHD, the transplanted cells reject the recipient's tissue as foreign and attack the tissue. GVHD in stem cell transplants appears to be less severe with umbilical cord blood, which appears to be more tolerant of the new body's environment. To reduce the risk of GVHD or tissue rejection, HLA testing is required. Order HLA testing online here.
Graft vs. Host Disease (In reference to BMTs)
Graft Versus Host Disease. A side effect of a bone marrow or stem cell transplant that occurs when new bone marrow or stem cells (the graft) reject or attack the patient's body (the host).
Graft-versus-Host Disease. Following transplantation of nonautologous, immune-competent lymphocytes, these cells induce a cellular immune reaction in the host organism[ back
Graft versus host disease. A patient's immune normally identifies 'foreign' cells in their body, such as bacteria or viruses, and attacks them, helping to protect against infection. Sometimes the patient's new immune system recognises the patient as different from the bone marrow donor. As a result the donor's white cells, living in the patient, will attack the patient (its host).
Graft-versus-Host Disease - a disease that occurs when the donor's bone marrow attacks the host/recipient's body as foreign; in its severe form, GVHD is often fatal.
Graft-versus-host disease. A reaction of donated bone marrow or peripheral stem cells against a person's tissue.
Graft vs. host disease. A collection of ailments that sometimes arises after bone marrow transplants, when the donor's immune system (the "graft") attacks various tissues (the gut, skin, etc.) of the patient.
Graft Versus Host Disease. A condition where the transplanted donor marrow or blood stem cells attack the patient's body. GVHD can be mild or serious and is sometimes life threatening.
Graft Versus Host Disease. a condition where transplanted cells from the donor attack the cells of the host's body. In the first 100 days, the tissues most likely to be attacked are the skin, GI tract , and the liver.
