Comparing genes expressed in healthy tissue with those expressed in diseased tissue can help identify proteins associated with the disease, narrowing the search for appropriate drug targets.
Analysis of the expression of mRNA or proteins in cells, tissues or organisms at different developmental stages, in disease, during drug treatment, etc.
A high-throughput method for evaluating the degree and timing of gene expression in a cell or tissue.
A method for comparing genes that are expressed in healthy tissue with those expressed in diseased tissue to identify proteins associated with the disease.
a powerful functional genomics tool, but suffers from a major limitation of discordance with protein expression levels
The search for genes expressed in specific tissues during normal or diseased states.
Microarray technology is often used for gene expression profiling. It makes use of the sequence resources created by the genome sequencing projects and other sequencing efforts to answer the question, what genes are expressed in a particular cell type of an organism, at a particular time, under particular conditions?
