Definitions for "Gene amplification"
Keywords:  oncogene, proto, copy, dna, genome
Increased replication of a gene.
a selective increase in the number of copies of a gene which codes for a specific protein without a proportional increase in other genes
A process of DNA duplication that results in a chromosome having more than one copy of a gene or genes and which can result in inappropriate gene activation. It is a common mechanism of activation of oncogenes such as erbB-2 and c-myc in breast cancer.
Keywords:  amplification, see
See amplification.