Multiple copies of a single gene within a cell.
Creation of multiple copies of a particular gene, allowing the production of large amounts of the RNA transcript (as in rRNA synthesis in oocytes).
Production of extra copies of a chromosomal sequence found either as intra- or extra-chromosomal DNA; with respect to a plasmid, it refers to the increase in the number of plasmid copies per cell induced by a specific treatment of transformed cells.
An increase in the number of copies of a DNA sequence. Can be used to increase the amount of a DNA sample to facilitate its analysis. See also Polymerase chain reaction.
An abnormal cellular event that results in a cell having a greater number of copies of a gene than normally present
Process in tumour cells of the production of multiple copies of certain genes, the visible evidence of which are homogeneously staining regions and double-minute chromosomes.
The process whereby genes or a sequence of DNA in the genome is greatly increased in number of copies.
To copy segments of genes within DNA or RNA.
Repeated copying of a piece of DNA; a characteristic of tumor cells. Source : Human Genome Project Information
The presence of multiple copies of a gene or segment of DNA; a mechanism by which proto-oncogenes are activated in malignant cells. A tumor cell amplifies, or copies, DNA segments as a result of cell signals or the effects of environmental insults.
Repeated copying of a piece of DNA; a characteristic of tumor cells. See also: gene, oncogene
An increase in the number of copies of any particular piece of DNA. A tumor cell amplifies, or copies, DNA segments naturally as a result of cell signals and sometimes environmental events.
any process by which specific dna sequences are replicated disproportionately greater than their representation in the parent molecules; during development, some genes become amplified in specific tissues.
The presence of multiple genes. One mechanism through which proto-oncogenes are activated in malignant cells - Not PCR
selective synthesis of DNA, causing multiple copies of a single gene to be made, thereby enhancing expression.
Increase in the normal copy number of a gene.
The process by which the number of copies of a chromosomal segment is increased in a somatic cell.