Restriction fragment length polymorphisms. Pieces of DNA produced by digesting genomic DNA with restriction endonucleases enzymes.

a sequence of DNA that has a restriction site on each end with a" target" sequence in between

restriction fragment length polymorphism. a technique in which organisms may be differentiated by analysis of patterns derived from cleavage of their DNA. If two organisms differ in the distance between sites of cleavage of a particular restriction endonuclease, the length of the fragments produced will differ when the DNA is digested with a restriction enzyme. For example, DNA from P. stutzeri KC has a unique RFLP pattern that differentiates it from other isolates in the aquifer.

An acronym for restriction fragment length polymorphism.

Restriction Fragment Length Polymorphism. See single nucleotide polymorphism.

Restriction fragment length polymorphism. A type of polymorphism detectable in a genome by the size differences in DNA fragments generated by restriction enzyme analysis. Read more about RFLPs references: Botstein D, et al. Construction of a genetic linkage map in man using restriction fragment length polymorphisms. Am J Hum Genet 1980; 32(3):314-31. Donis-Keller H, et al. A genetic linkage map of the human genome. Cell 1987; 51(2):319-37.

restriction fragment length polymorphism; a technique using small bits of DNA fragments linked to various diseases.

Restriction fragment length polymorphism. Variation in the length of a stretch of DNA.

Restriction fragment length polymorphism. Variation in DNA sequence between individuals that is detectable by variation in the length of DNA fragments generated by digestion with restriction endonucleases.

restriction fragment length polymorphism. A heritable difference in DNA fragment length and fragment number; passed from generation to generation in a codominant way.

See Restriction Fragment Length Polymorphism (RFLP)

Restriction fragment length polymorphism. Variation in the distance between restriction enzyme cleavage sites that exist within a population producing unique DNA fingerprint patterns.

RFLP mapping detects patterns in DNA that can indicate the presence of a gene for a trait. Both RFLP and polymerase chain reaction (PCR) analysis can be used in DNA fingerprinting for genealogical studies and forensics.

considered to be the most accurate DNA test; it takes several weeks to complete, and is becoming more frequently used in forensics cases.

(restriction fragment length polymorphism) variations occurring within a species in the length of DNA fragments generated by a specific restriction endonuclease. Such variation is generated either by base substitutions that cause gain or loss of sites, or by insertion/deletion mutations that change the length of fragments independent of restriction site changes.

Coexistence of two or more patterns of restriction fragments (patterns produced by restriction enzymes), as revealed by a probe. The polymorphism reflects a difference in DNA sequence on homologous chromosomes.

Restriction fragment length polymorphism. A mutation that results in a detectable change in the pattern of fragments obtained when a DNA molecule is cut with a restriction endonuclease.

Restriction fragment length polymorphism. A difference in restriction fragment length between individuals due to loss or gain of a restriction enzyme site due to point mutation, or insertion or deletion between consecutive sites. Normally detected by Southern blotting and probing. Used in detection of genetic disease alleles etc.

Restriction Fragment Length Polymorphisms. Length differences associated with strands of DNA. These differences vary from person to person, thus providing a means to further identify DNA.

restriction fragment length polymorphism. Variation between individuals in DNA fragment sizes cut by specific restriction enzymes; polymorphic sequences that result in RFLPs are used as markers on both physical maps and genetic linkage maps.

(Restrictriction Fragment Length Polymorphism) Differences in nucleotide sequence between alleles at a chromosomal locus result in restriction fragments of varying lengths detected by Southern analysis.

Restriction fragment length polymorphism. Variations between individuals in DNA fragments that are recognised as cutting sites by specific restriction enzymes. Used as markers in chromosome mapping.

Restriction fragment length polymorphism. Differences in DNA sequence on homologous chromosomes that result in restriction fragments of varying lengths that can be detected using DNA probes.

Restriction Fragment Length Polymorphism. An old method of forensic DNA analysis based on the different sized fragments that can be produced when a piece of DNA is cut by certain enzymes. Replaced by STR analysis due to the large amount of DNA required for it to work, as well as the long time needed for analysis.

Restriction fragment length polymorphism. At some chromosomal locations a probe sometimes detects different sizes or different numbers of restriction fragments (often as a result of presence and absence of restriction sites), and this situation is an RFLP. If an individual is heterozygous for such a chromosomal difference, that region can be used as a marker in chromosome mapping.

Restriction fragment length polymorphism. refers to inherited differences in sites for restriction enzymes between two related DNA sequences (for example, caused by base changes in the target site) that result in differences in the lengths of the fragments produced by cleavage with the relevant restriction enzyme. RFLPs are used for genetic mapping to link the genome directly to a conventional genetic marker.

Variation between individuals in DNA fragment sizes cut by specific restriction enzymes; polymorphic sequences that result in RFLPs are used as markers on both physical maps and genetic linkage maps. RFLPs are usually caused by mutation at a cutting site.

Restriction fragment length polymorphism. RFLPs are generated by digesting DNA with restriction enzymes. The DNA is separated by size by gel electrophoresis. Slight differences in homologous fragments may exist between individuals. These length polymorphisms are RFLPs. See blot.

Restriction Fragment Length Polymorphism. A technique used in the process of DNA profiling.

Restriction Fragment Length Polymorphism. A change in the DNA of an organism that changes how a restriction enzyme cuts the DNA into pieces. Two or more organisms can be compared based on the pattern of their DNA fragments when they are run on a gel (by electrophoresis). If the organisms have different spaces between their restriction enzyme sites, they produce different lengths of fragments when the restriction enzyme is used to cut up the DNA. When their fragments are run on a gel, they produce different patterns because the shorter fragments will move further than the longer ones.

Restriction fragment length polymorphism. The detection of variations in DNA sequence in populations by cleaving DNA with restriction enzymes and analyzing the patterns of the resulting DNA fragments.

Restriction Fragment Length Polymorphism. A DNA variation that affects the distance between restriction sites (most often by a nucleotide change that creates or eliminates a site) within or flanking a DNA fragment recognized by a cloned probe (see Chapter 8). RFLPs are detected upon Southern blot hybridization. The term RFLP is commonly used even in situations where the DNA variation may not represent a true polymorphism in the population-based definition of this term. See RFLP in the MGI Glossary.

Restriction Fragment Length Polymorphism. Polymorphisms on the DNA molecule detected by variations in restriction fragments generated by treatment with restriction enzymes.

Restriction fragment length polymorphism. A variation in DNA sequence that is easily recognized because it occurs at a site where a restriction enzyme cuts a specific sequence, producing DNA fragments of varying lengths. RFLP's often serve as genetic markers.

Restriction fragment length polymorphism is a process used in DNA identification testing in which size (fragment length) differences at specific regions of the DNA are detected.

Restriction Fragment Length Polymorphism. Variations in the size of DNA fragments produced by a restriction endonuclease at a polymorphic locus.

Restriction Fragment Length Polymorphism (RFLP) is a codominant type of molecular genetic marker based on differences in restriction enzyme digestion patterns between individuals.

estriction ragment ength olymorphism. Inherited differences in sites for restriction enzymes (e.g., caused by base changes in the target site) that result in differences in the lengths of the fragments produced by cleavage with the relevant restriction enzyme. RFLPs are used for genetic mapping to link the genome directly to a conventional genetic marker. ( 13)

Restriction Fragment Length Polymorphism. Restriction fragment length polymorphism (RFLP) is a variation in electrophoresis banding patterns of specific DNA fragments from different individuals of a species. RFLP is caused by the presence of a restriction enzyme cleavage site at one place in the genome of one individual and the absence of that specific site in another individual (a restriction enzyme recognizes a specific target nucleotide sequence in DNA and breaks the DNA chain at that target).

Restriction fragment length polymorphism; a fragment resulting from restriction-enzyme digestion of DNA.