A mutation that causes the formation of a nonsense codon and the truncation of the protein product.
A mutation in which a codon is changed to a stop codon, resulting in a truncated protein product.
a mutation in which one of the three terminator codons (used to signal the end of a polypeptide) in messenger RNA appears in the middle of a genetic message, causing premature termination of transcription, resulting in the production of generally nonfunctional polypeptides.
A mutation that changes an amino acid specifying codon to one of the three termination (stop) codons.
Nucleotide substitution that creates a stop codon. ATG GTG AA GTA... (MetValLysVal...) to ATG GTG AA GTA would result in a truncated protein (MetVal), most likely to be non-functional
A mutation which converts an amino-acid-specifying codon into a stop codon, e.g., a change from UAU (tyr) to UAG (amber) would lead to the premature termination of a polypeptide chain at the place where a tyrosine was inserted in the wild-type. See stop codon; suppressor.
Mutations that change a codon for an amino acid to one of the codons (UAG, UAA, or UGA) that signal termination of translation. The resulting gene product is a shortened polypeptide that begins normally at the amino-terminal end and ends at the position of the altered codon. (Contrast with frame-shift mutation, missense mutation, synonymous mutation.)
Mutation in coding DNA that prevents the protein from being synthesized.
a change in one DNA base pair
a change in the genetic sequence which changes a codon from an amino acid to a stop codon
a mutation that replaces a codon for an amino acid with one of the three stop codons
A type of gene mutation that introduces an inappropriate ‘stopâ€(tm) signal into the DNA sequence, resulting in a shortened protein.
NON-sents mu-TAY-shun A point mutation that alters a codon that encodes an amino acid to one that encodes a stop codon. 341
a single DNA base pair change which results in a premature stop codon; a truncated protein may be produced
A substitution of one of the bases of DNA that results in a stop codon.
Any mutation (substitiution, addition or deletion) that changes an amino acid specifying codon into a chain terminating codon.
A single DNA base substitution resulting in a stop codon.
A single base pair substitution that prematurely codes for a stop in amino acid translation (stop codon)
Substitution of a single DNA base that results in a stop codon, thus leading to the truncation of a protein.
Base pair change in DNA that changes a codon into a chain-terminating codon.
A type of mutation that changes an amino acid codon to one of the three stop codons, resulting in a shorter and usually nonfunctional protein.
A mutation that changes a sense codon into one which does not code for an amino acid.
is any change in DNA that causes a (termination) codon to replace a codon representing an amino acid.
Any change in DNA that results in a three-base-pair sequence that does not code for an amino acid and thus terminates the protein sequence.
A mutation that changes a triplet coding for an amino acid into a termination codon.
A truncated mutation....the protein is truncated by mutation, and so dysfunctional or non-existent depending on where the mutation occurs.
mutation that alters a gene so as to produce a .
In genetics, a nonsense mutation is a point mutation in a sequence of DNA that results in a premature stop codon, or a nonsense codon in the transcribed m RNA, and possibly a truncated, and often nonfunctional protein product.