An enzyme which catalyzes creation of a covalent bond between two substrates, resulting in a larger product which is a combination of the two starting materials; especially, DNA ligase, an enzyme which creates a phosphate bond between 5´ and 3´ ends of a DNA chain, resulting in a longer chain of DNA. DNA ligase is important in normal biosynthesis of DNA in the replication cycle of cells.
An enzyme used to catalyze the joining of single-stranded DNA segments.
an enzyme used to splice DNA fragment to another DNA molecule.
enzyme that catalyzes the joining of two free ends of nucleic acid strands. DNA ligase is necessary for DNA replication and is used in recombinant DNA technology to join separate DNA fragments.
An enzyme or ribozyme that adds a monomer to a polymer, or links two shorter polymers together.
An enzyme that repairs single-stranded discontinuities in double-stranded DNA molecules in the cell. Ligase joins a 3'-OH residue of a deoxyribonucleotide to the 5'-phosphate residue of an adjacent deoxyribonucleotide. Purified DNA ligase is used in gene cloning to join DNA molecules together.
An enzyme that catalyzes a condensation reaction that links two DNA molecules via the formation of a phosphodiester bond between the 3' hydroxyl and 5' phosphate of adjacent nucleotides.
An enzyme, T4 DNA ligase, which can link pieces of DNA together. The pieces must have compatible ends (both of them blunt, or else mutually compatible sticky ends), and the ligation reaction requires ATP.
In genetics, the general term for a class of enzymes that speed up the joining of the ends of two chains of DNA.
An enzyme that joins two molecules together covalently, e.g. D-alanine ligase, which forms D-alanyl-D-alanine from two D-alanine molecules.
An enzyme that catalyzes the formation of phosphodiester bonds in DNA. The enzyme from T4 bacteriophage is widely used in recombinant DNA work.
An enzyme that ligates (joins) two molecules in an energy-dependent process.
Enzyme that joins together (ligates) two molecules in an energy-dependent process. DNA ligase, for example, links two DNA molecules together through a phosphodiester bond.
a bacterial enzyme that seals any breaks in the DNA molecule
a commercially available enzyme and the conditions for its use in the manne indicated are well known in the art
an enzymatic protein that functions to ligate together long chain fatty acids, a function that plays important roles in a variety of different physiological processes
an enzyme that can join (ligate) DNA molecules together
an enzyme that repairs broken DNA strands
an enzyme which catalyzes such a reaction
an enzyme which serves as a genetic glue, welding the sticky ends of exposed nucleotides together
a recombinant enzyme formulated and tested for high activity
a specific enzyme involved in the utilization of PAA as energy source
An enzyme that joins together DNA segments.
An enzyme that is used to join fragments of DNA together, for example in gene splicing. Ligase is used in recombinant technology.
A joining enzyme which closes single-strand breaks in DNA.
An enzyme used to join DNA or RNA segments together. They are called DNA ligase or RNA ligase, respectively.
an enzyme which is capable of catalyzing the ligation (tying together) of two free ends of a nucleic acid molecule.
an enzyme that catalyzes the formation of a phosphodiester bond between adjacent 3'-OH and 5'-P atoms in DNA
An enzyme that connects two nucleic acids to form a single continous nucleic acid.
An enzyme that can rejoin a broken phosphodiester bond in a nucleic acid.
An enzyme that links together the 3 end of one nucleic acid strand with the 5 end of another, forming a continuous strand.
In biochemistry, a ligase (from the Latin verb ligÄre — "to bind" or "to glue together") is an enzyme that can catalyse the joining of two large molecules by forming a new chemical bond, usually with accompanying hydrolysis of a small chemical group pendant to one of the larger molecules.