Definitions for "Streptomycin"
An antibiotic that inhibits protein synthesis in bacteria by binding to the S12 protein of the 30s ribosomal subunit and inhibiting translation. A high level of StrR can result from chromosomal mutations in the gene for the S12 protein ( rpsL) which prevent streptomycin from binding to the ribosome. Only mutant ribosomes are StrR, so resistance to streptomycin is recessive to streptomycin sensitivity. Because streptomycin rapidly inhibits protein synthesis, when cells acquire the rpsL gene phenotypic expression is required before the cells become streptomycin resistant.
Aminoglycoside antibiotic, binds 30S subunit of bacterial ribosome and causes ribosome misreading. (Lecture: Antibiotics and Antibiotic Resistance, 2/12/02)
An antibiotic produced by the soil actinomycete Streptomyces griseus. It acts by inhibiting the initiation and elongation processes during protein synthesis.
an injectable drug used to treat TB disease; may cause hearing problems; should not be given to pregnant women.