A class of antibiotic drugs often used for selective ablation of the vestibular endorgan. Examples are streptomycin and gentamicin; both have their main toxic effects on vestibular hair cells and dark cells, and to a lesser extent, on cochlear hair cells.

Aminoglycosides are a group of antibiotics that are effective against certain types of bacteria. They include amikacin, gentamicin, kanamycin, neomycin, netilmicin, paromomycin, streptomycin, tobramycin and apramycin. Those which are derived from Streptomyces genus are named with the suffix -mycin, while those which are derived from micromonospora are named with the suffix -micin.