A basophil that has migrated into loose connective tissue which secretes heparin (an anticoagulant) and seratonin (promotes inflammation).

Widely distributed tissue cell that releases histamine as part of an inflammatory response. Closely related to blood basophils.

a type of cell present in most body tissues that releases substances in response to an allergen, which causes symptoms such as inflammation

A basophil or a true tissue cell.

A cell that is derived from the pluripotential lymphohematopoietic stem cell. It traverses the blood in such small numbers that it is not recognized as a blood cell. It enters the tissues and in those sites is apparent because of its large and numerous granules, which when stained in slides of tissue samples have a characteristic deep blue-purple color. In allergic reactions, it is the source of histamine and other chemicals that causes many of the symptoms of allergy.

Connective tissue cell whose specific physiologic function remains unknown; capable of producing cytoplasmic granules that contain histamine, heparin.

A specialized cell found in tissues. It causes allergic reactions when activated by allergens that bind to IgE antibodies on the cell surface. Activation of the cell is followed by release of histamine and other substances that cause symptoms of allergy.

A connective tissue cell that, when stimulated, releases histamine, serotonin, and heparin, initiating the inflammatory response.

a large connective tissue cell that contains histamine and heparin and serotonin which are released in allergic reactions or in response to injury or inflammation

(maast sell) - a cell in your body that takes part in allergic reactions. It is in all different parts of the body such as the nose and skin.

A cellular component of the immune system that resides in tissue. When attached to an IgE-Antibody combination, releases mediators of allergic reactions, including leukotrienes, histamine and other mediators.

A type of cell, found mostly in the connective tissue in the body, that produces histamine when you are exposed to an allergen. (See definitions for histamine and allergen.)

Type of leukocyte (white blood cell) found in connective tissues that produces histamine and other inflammatory molecules

Originates in the bone marrow; involved in allergic responses.

A granulated cell found abundantly in the skin and the gastrointestinal tract. Mast cells contain large amounts of histamine and heparin, but unlike basophils, they normally remain in the tissues and do not circulate in the blood. Mast cell degranulation (dumping out the contents of internal granules) can cause the symptoms of a severe allergic reaction (anaphylaxis).

Cell found in connective tissues containing inflammatory mediators (e.g. histamine) in basophilic granules.

A type of immune system cell present in blood and tissue.

A non-circulating leukocyte characterized by histamine-filled granules. Mast cells are involved in hypersensitivity reactions.

An immune system cell which attaches to antibodies and is located in the tissue that lines the nose, bronchial tubes, gastrointestinal tract, and the skin

a white blood cell which causes inflammation durring an allergic response.

an IMMUNE SYSTEM cell filled with granules of inflammatory chemicals such as histamine. This cell is believed to play a leading role in generating the symptoms of allergy.

A type of white cell that is involved in the allergic reaction. These cells release chemicals such as histamine.

A specialized, granule-containing cell found in the skin and lining of the inner body surfaces; it plays a central role in the development of allergy.

Mast cells play an important role in the body's allergic response. Mast cells are present in most body tissues, but are particularly numerous in connective tissue, such as the dermis (innermost layer) of skin. In an allergic response, an allergen stimulates the release of antibodies, which attach themselves to mast cells. Following subsequent allergen exposure, the mast cells release substances such as histamine (a chemical responsible for allergic symptoms) into the tissue.

connective tissue cell whose normal function is unknown but which is frequently injured in allergic reactions, releasing chemicals including histamine that are very irritating and cause itching, swelling, and fluid leakage from cells. These allergic chemicals may also cause muscle spasm and lead to lung and throat tightening, as in asthma. Also known as a mastocyte or labrocyte.

a tissue cell that is a primary participant in immediate hypersensitivity reactions. Mast cells make and release histamine and other mediators of inflammation.

a connective tissue cell that contains coarse storage granules; the cell is believed to store and release heparin, histamine, and serotonin.

A type of white blood cell.

A granule-containing cell found in tissue. The contents of mast cells, along with those of basophils, are responsible for the symptoms of allergy.

Tissue located cell probably derived from basophils. Possesses receptor for Fc of IgE. Participates in 'Immediate hypersensitivity' reactions.

A granulocyte found in tissue. The contents of the mast cells, along with those of basophils, are responsible for the symptoms of allergy. See also Basophil; Granulocyte.

Dermal cell which releases histamine and heparin (substances acting in response to a skin flare to redden the skin). These are a group of cells that line the capillaries of tissues that come in contact with the outside, like skin, sinuses, and lung mucosa.

A type of large cell abundant in the mucosa, skin, the lining of the gut, and the airways. Mast cells play a key role in allergic reactions by releasing histamine, leukotrienes, and other inflammatory mediators (see Allergies).

A mast cell (or mastocyte) is a resident cell of areolar connective tissue(loose connective tissue) that contains many granules rich in histamine and heparin. Although best known for their role in allergy and anaphylaxis, mast cells play an important protective role as well, being intimately involved in wound healing and defense against pathogens.