a toxic amino acid (a bad guy) that is present in all humans
A metabolite of methionine that is converted to the benign cystathionine by a B6-dependent enzyme. Homocysteine has been implicated in the pathogenesis of heart disease.
a sulfur-containing amino acid formed during methionine metabolism; 70% to 80% of homocysteine forms disulfide bonds with sulffiydryl groups of plasma proteins and thus becomes a protein-bound fraction
Homocysteine is a sulfur-containing amino acid found in blood. Studies have linked elevated levels of blood homocysteine to atherosclerosis.
An amino acid produced during metabolism of another amino acid called methionine. Homocysteine is regarded as a risk factor for heart disease and is implicated in other disease conditions
Homocysteine is an amino acid in the blood. Studies have shown that too much homocysteine is related to a higher risk of coronary heart disease, stroke and peripheral vascular disease. Other evidence suggests that homocysteine may damage the inner lining of arteries and promote blood clots. Homocysteine levels are strongly influenced by diet, as well as genetic factors. The dietary components with the greatest effects in reducing your homocysteine levels are folic acid and vitamins B6 and B12. Folic acid and other B vitamins help break down homocysteine in the body. Several studies have found that higher blood levels of B vitamins are related, at least partly, to lower concentrations of homocysteine.
Researchers believe that homocysteine may contribute to the build-up of fatty substances in the arteries, increase the stickiness of blood platelets (clotting), and make blood vessels less flexible and less able to widen to permit increased blood flow.
amino acid by-product of methionine metabolism.
an amino acid (a building block of protein) that is produced in the human body
An amino acid that is found normally in the body. Recent studies suggest that high blood levels of this substance may increase a person's chances of developing heart disease, stroke and reduced blood flow to the hands and feet. It is believed that high levels of homocysteine may damage the arteries, make the blood more likely to clot and/or make blood vessels less flexible. Homocysteine levels are affected by the consumption of three vitamins - folic acid and vitamins B6 and B12. People who consume less than the recommended daily amounts of these vitamins are more likely to have higher homocysteine levels. Recommended daily amounts are as follows: 400 micrograms of folic acid, 2 milligrams of B6, and 6 micrograms of B12. It has not yet been proven that lowering homocysteine levels will actually help prevent heart or blood vessel disease.
An amino acid-like substance; high levels have been linked to heart disease.
An amino acid found in the blood. High homocysteine levels are a risk factor for blood clots in the veins (DVT, PE) or arteries (heart attack, stroke), and hardening of the arteries (arteriosclerosis).
An amino acid in the blood. There is evidence that a high level of homocysteine may be associated with an increased risk of developing atherosclerosis. Blood homocysteine levels may be lowered by eating foods rich in folic acid, such as green leafy vegetables and fruits.
An amino acid used normally by the body in cellular metabolism and the manufacture of proteins. Elevated concentrations in the blood are thought to increase the risk for heart disease by damaging the lining of blood vessels and enhancing blood clotting.
An amino acid in the blood. Elevated plasma levels may lead to increased risks of PAD.
a product which is found naturally when a particular amino acid is broken down. It is associated with ageing, folate levels, vitamin B deficiencies and possibly renal dysfunction. Higher concentration of homocysteine in plasma is regarded as a risk factor for cardiovascular disease
Homocysteine is an amino acid derived from the digestion of protein-rich foods.
An amino acid. Elevated blood levels of homocysteine have been linked to increased risk of premature coronary artery disease and stroke, even among people who have normal cholesterol levels.
An amino acid formed when other amino acids in your blood are broken down by normal body processes. Too much homocysteine in your blood can cause heart disease. Folic acid breaks down the homocysteine and prevents a toxic buildup.
An amino acid that occurs naturally in the body. High levels are a risk factor for coronary artery disease. Homocysteine helps "bad cholesterol" ( LDL) build fatty plaques in the coronary arteries.
Homocysteine is considered a marker for the increased chance of a heart attack. Controversy exists as to whether high levels of homocysteine are the cause of the heart attacks or just a symptom of other factors that cause heart attacks. Vitamin B6 (especially pyridoxamine), folic acid and vitamin B12 in combination are able to reduce homocysteine levels significantly. Each of these vitamins have other functions which have significant effect on the formation of AGEs and oxidation products. These other functions may play a more important role in heart disease than dose the reduction of homocysteine. The jury is still out on this one, we will have to wait for the correct answer.
a sulfhydryl-containing amino acid derivative that normally undergoes rapid enzymatic metabolism and is thus present at only low levels in plasma. Plasma concentration is influenced by levels of folic acid, vitamin B12 and vitamin B6 in the diet, the total methionine (an amino acid) content of dietary intake, presence of certain genetic polymorphisms (CBS, MTHFR, MS), age and gender.
An amino acid in the blood. Studies have shown that too much homocysteine in the blood (plasma) is related to a higher risk of coronary heart disease, stroke and peripheral vascular disease.
An amino acid in the blood that has been linked to heart disease and stroke. Folic acid and vitamins B6 and B12 have been shown to break down homocysteine in the body.
An amino acid that in high levels has been linked to heart disease.
An amino acid produced by the body, usually as a byproduct of consuming meat. Homocysteine is made from another amino acid, methionine, and then in turn is converted into other amino acids. See the entire definition of Homocysteine
A type of amino acid that forms proteins necessary for human life.
an amino acid produced by the breakdown of methionine (protein) in the body
An amino acid metabolite of the essential amino acid, methionine. Homocysteine usually occurs transiently before conversion to harmless cystathionine via a vitamin B6 dependent enzyme. High levels of homocysteine in the blood are strong indicators of cardiovascular disease, as well as B-complex vitamin deficiency.
A toxic waste product produced during cellular metabolism. This amino acid that is believed to damage cells that line arteries. A high blood homocysteine level correlates with early, serious heart disease. (High Intake of 2 B vitamins – B-6 and Folate– may lower risk by lowering homocysteine levels. The study was based on taking 400 micrograms folate and 3 mg. of B-6 daily.) hydrogenation A process that adds consistency to a product that would otherwise be fairly liquid, such as solid cooking oils and stick margarines. Hydrogenation produces trans-fatty acids (sometimes called trans-fats).
A substance produced as the body digests protein. While normal levels of homocysteine help build and maintain tissues in the body, high levels may add to blood vessel damage caused by cholesterol or other substances. Damaged blood vessels are more likely to narrow or close completely, which can lead to heart disease or stroke.
An amino acid that circulates in the blood. People who have elevated homocysteine levels are at increased risk of arterial blockage, resulting in a heart attack or stroke. Normally, three of the B vitamins (folate, vitamin B[6] and vitamin B[12]) assist in the conversion of homocysteine into other non-damaging amino acids.
Homocysteine is an amino acid in the blood. Epidemiological studies have shown that too much homocysteine is related to a higher risk of coronary heart disease, stroke and peripheral vascular disease. Other evidence suggests that homocysteine may have an effect on atherosclerosis by damaging the inner lining of arteries and promoting blood clots. However, a direct causal link hasn't been established. Homocysteine levels are strongly influenced by diet, as well as by genetic factors
An amino acid that results from methionine breakdown in the body. There is evidence that a high level of homocysteine in the blood is associated with an increased risk of developing coronary artery disease. Vitamins B6, B12 and folic acid play a role in the maintenance of normal homocysteine levels.
A group of corresponding amino acids found in proteins.
A sulfur containing amino acid. Considered a risk factor for cardiovascular disease and possibly neurodegeneration.
Homocysteine is the chemical compound with the formula HSCH2CH2CH(NH2)CO2H. It is a homologue of the naturally-occurring amino acid cysteine, differing in that its side-chain contains an additional methylene (-CH2-) group before the thiol (-SH) group. Alternatively, homocysteine can be derived from methionine by removing the latter's terminal Cε methyl group.