a protein that stimulates the growth of blood vessels. There are several types encoded by different genes (e.g. VEGF A, VEGF B) and each has several different isoforms encoded by different splice variants of that particular gene.

(VEGF) A growth factor (or local hormone) needed for new blood vessels to form in, for example, the corpus luteum, as it turns into an efficient hormone-producing gland making and releasing progesterone about a week after ovulation. Because such new blood vessels are rather leaky, excess VEGF from multiple corpora lutea during ovulation induction or superovulation using gonadotropins can be associated with new blood vessels trying to form in the general peritoneal cavity, leakage of fluid from which causes fluid to build up in the abdomen, a potentially dangerous condition known as the ovarian hyperstimulation syndrome. VEGF is also important in the formation of the placenta, so mutations of VEGF or its target proteins can cause recurrent miscarriage.

One of the major growth factors that promotes the growth of new blood vessels (angiogenesis).