Normal cellular genes that, when mutant or overactive, contribute to cancerous transformation in cells.
The normal alleles of genes possessing oncogenes (cancer-causing genes) as mutant alleles. Proto-oncogenes encode growth factors and receptor proteins.
fragments of genetic material (DNA), related to oncogenes, but are the normal "switches" used to control growth and tissue repair.
Genes that tell a cell to enter the cell cycle and control when a cell should divide. If a proto-oncogene loses the ability to regulate the cell cycle, the cell may divide uncontrollably. Proto-oncogenes can become damaged and become a cancer gene (oncogene).
A gene that promotes normal cell growth and differentiation.
Cellular genes which, when mutated, or over-expressed become oncogenes.
Normal segments of DNA (genes) in cells that code for proteins involved in cell cycle regulation and DNA repair. Proto-oncogenes are capable of being transformed into oncogenes, which can contribute to cells becoming malignant.
genes that code for growth factors. They are capable of undergoing mutation when they form oncogenes. Oncogenes cause unregulated growth and proliferation of cells
