This Native American grape grows in the South East of the country, it is primarily grown for table grapes but is sometimes used to make wine; particularly the variety Scuppernong, which is still sometimes used to make sweet wines .

Muscadines (Vitis rotundifolia) are a grapevine species native to the present-day southeastern United States that has been extensively cultivated since the 16th Century. They are well adapted to their native warm and humid climate; they need fewer chilling hours than better known varieties and they thrive on summer heat.