A molecule or ion that is bound to protein.

a small molecule that binds to a larger molecule, for example a molecule that binds to a receptor or an antigen that binds to an antibody.

a negative ion or polar molecule attached to a central ion in a complex ion.

A small molecule (e.g. activators, substrates and inhibitors of enzyme activity) bound to a protein by non-covalent forces; an ion or a molecule that binds to another chemical entity to form a larger complex.

a molecule (such as oxygen) that binds to a complementary site on a given structure (such as hemoglobin).

A ligand is a molecule that can form a bond with a (transition) metal atom, resulting into a (transition) metal complex. Such a complex can act as a catalyst.

A small molecule that binds specifically to a larger one; for example, a hormone is the ligand for its specific protein receptor.

(lih-gand or lie-gand) A molecule that binds to another molecule; in the case of VEGF antibody, both VEGF and the antibody are considered ligands; a ligand may also bind to a receptor.

A molecule that can bind to another molecule in or on cells.

Ligand is an ion (F-, Cl-, Br-, I-, S2-, CN-, NCS-, OH-, NH2-) or molecule (NH3, H2O, NO, CO) that donates a pair of electron to a metal atom or ion in forming a coordination complex.

A Lewis base coordinated with a metal atom or ion to form a coordination complex

An ion or molecule which bonds to a metal ion to form a complex, but which can exist in its own right in the absence of the complex.

(Latin, ligare = to bind) A molecule that binds to a specific binding site in a protein.

receptor interaction The interactions between a molecule (usually of an extracellular origin) and a protein on or within a target cell. One type of ligand receptor interaction can be between steroid hormones and their cytoplasmic or nuclear receptors. Another can be between secreted polypeptide ligands and transmembrane receptors.

the most common application of this term is that it is the species surrounding a central dissolved ion in a solution, e.g., in the dissolved complex CuCl65-, the six Cl- ions are ligands surrounding a central Cu+ cation.

A ligand is any molecule or ion that has a lone pair that it may donate to a metal cation. See also: Coordination Complex

A molecule that binds non-covalently to another type of molecule.

(1) The smaller of two molecules that interact reversibly to form a complex. (2) A molecule that binds to a cell-surface receptor. (3) A molecule or ion that binds to a metal ion by donation of an electron pair.

A molecule that binds to a specific site on another molecule. Usually, the ligand is a hormone and the molecule to which it binds is a receptor. Example: insulin is the ligand for the insulin receptor.

is a substance that binds to a membrane receptor or ion channel. Most ligands are either neurotransmitters, hormones or drugs

A small molecule that binds another larger molecule, usually called a receptor. The binding event can change the receptor's conformation or activity, triggering subsequent biochemical reactions inside a cell, or in some cases, blocking subsequent biochemical reactions. Ligands that activate receptors are called agonists. Ligands that block receptor activity are called antagonists. For cancer, major therapeutic targets would include creating ligands that can interact with receptors to block cell growth or migration, or those that can activate immune responses against tumor components. See also Conservation, Receptor, Systems Biology.

A molecule or other chemical grouping attached to a larger molecular structure. In the case of a small molecule that binds to a biomacromolecule, the latter is frequently referred to as the "receptor."

The ion or molecule which surrounds or complexes with the central atom or ion.

A molecule which binds to a receptor molecule, producing a response (closing an ion channel, transmitting a signal inside the cell etc.)

A specific molecule which binds to a receptor, usually with high affinity.

molecule capable of binding to a receptor on the surface of the cell – may function as an agonist or an antagonist.

an atom or molecule or radical or ion that forms a complex around a central atom

a compound that specifically binds to a target molecule

a general term used to define a molecule to which another molecule binds

a molecule that binds specifically to a receptor site of another molecule

a molecule that binds to another chemical entity to form a larger complex, like the agglutination of blood group antigens by lectins

a molecule that binds to, complexes with, or reacts with a moiety of a cell population sought to be therapeutically or otherwise biologically modified

a molecule that can bind and unbind to a protein

a molecule which exhibits affinity for another molecule

a molecule which has unshared electron pairs

an atom, ion or molecule capable of functioning as the donor portion in one or more coordinate bonds

an electron pair donor (a Lewis base) that can bind to a metal ion via a weak covalent bond

an extracellular molecule that binds to the receptor on the plasma membrane of a cell, thereby effecting a change in the cytoplasm

a small molecule, or a small portion of a larger molecule, that binds to a RECEPTOR

a small molecule, such as a drug, that can bind to a protein or nucleic acid

a substance which is capable of binding specifically and reversibly with a binder

a transmitter substance or molecule that "fits" and evokes a response from a receptor

molecule which binds to a receptor to form a complex.

anything that binds to the receptor site of a molecule.

A linking or binding molecule that binds to a specific complementary site on (forms a complex with) another molecule. For example, a growth factor is a ligand for its growth factor receptor.

The molecule that binds to a specific receptor

molecule or ion connected to the central atom of a complex via a coordinating bond

A small molecule that binds to another larger molecule.

See complexing agent. Also, an unspecified organic chemical species.

a molecule, such as an antibody, hormone, or drug that binds to a receptor

an atom or group of atoms which is associated with a metal atom in a complex. Ligands may be neutral or they may be ions. (see: complex, ion)

A chemical which binds to a receptor.

A molecule or ion bonded to a central metal atom or ion in a coordination compound.

A chemical which binds somewhere; e.g., a "sigma ligand" is a drug which binds to sigma receptors somewhere. Ligands can be agonists or antagonists (or neither).

A molecule e.g. protein that is capable of recognizing and binding to a second molecule.

A small molecule that binds to a receptor/protein.

Any small molecule that binds to a protein or receptor; the cognate partner of many cellular proteins, enzymes, and receptors.

a molecule that forms part of a complex.

The molecule which binds to a protein molecule (e.g., receptor). As a ligand binds through the interaction of many weak, noncovalent bonds formed to the binding site of a protein, the tight binding of a ligand depends upon a precise fit to the surface-exposed amino acid residues on the protein.

The molecule, ion, or group bound to the central atom in a chelate or a coordination compound.

any atom/anion(-)/molecule which is currently (or capable of) bonding to a metal atom/cation to form a 'complex' with that metal atom/ion (eg. water molecule, CO molecule, chloride ion, hydroxide ion, ammonia molecule).

A molecule that binds to cell receptors

chemical messenger that fits into a receptor in order to communicate with a cell; for example, histamine binds to the H receptor to tell the parietal cell to begin acid secretion

a molecule that binds specifically to a protein. The term can also be used to mean a chemical substance that forms a coordination complex with a transition metal ion.

any molecule that binds to the surface of another molecule, such as an immune cell RECEPTOR. For examples of receptors see CCR5, CXCR-4, CD4.

In ligand-exchange chromatography, it is the molecule added to the mobile phase that acts as the chelating agent. In affinity chromatography, it is the biospecific material (enzyme, antigen, or hormone) coupled to the support (carrier) to form the affinity column.

A soluble molecule such as a hormone or a neurotransmitter which binds to a receptor

Binding partner

Small molecules that are attached to larger molecules. A fluorescent reporter dye attached to a oligonucleotide is a ligand.

General term for a molecule recognized by a binding structure such as receptor.

Any molecule that binds to a specific site on a protein or other molecule.

A Lewis base in a coordination compound.

In protein chemistry, a small molecule that is (or can be) bound by a larger molecule is termed a ligand. In organometallic chemistry; moiety bonded to a central metal atom is also termed a ligand; the latter definition is more common in general chemistry.

any molecule that binds to a specific binding site on an enzyme or receptor.

An agent with a strong affinity to a metal ion

Any atom or molecule attached to a central atom, usually a metallic element, in a coordination or complex compound. The atoms and molecules used as ligands are almost always those that are capable of functioning as the electron-pair donor in the electron-pair bond (a coordinate covalent bond) formed with the metal atom.

An ion, a molecule, or a molecular group that binds to another chemical entity to form a larger complex.

a molecule or ion that binds to a metal atom or ion through coordination of its lone electron pairs. A coordination complex is formed when a metal ion is surrounded by a group of ligands.

A molecule that binds to another molecule, used especially to refer to a small molecule that binds specifically to a larger molecule, e.g. an antigen binding to an antibody hormone or neurotransmitter binding to a receptor, or a substrate or allosteric effector binding to an enzyme. Ligands are also molecules that donate or accept a pair of electrons to form a coordinate covalent bond with the central metal atom of a coordination complex. [MeSH] Related term binding site. Pharmaceutical biology glossary Related terms Drug Discovery & Development glossary

A molecule or ion that can form a complex with another molecule, usually a macromolecule. Also, an organic molecule capable of forming coordinate covalent bonds with metallic ions. Can be natural or synthetic in origin.

Chemical agent, neurotransmitter or hormone, that directly or indirectly activates ion channels (ligand-gated) to permit or block movement of specific ions across membranes. See also ligand-gated channels, non-gated channels, voltage-gated channels.

Any chemical that binds to a receptor. Ligands may be agonists or antagonists.

Any molecule, other than an enzyme substrate, that binds tightly and specifically to a macromolecule, usually a protein, forming a macromolecule-ligand complex.

In chemistry, a ligand is an atom, ion, or molecule (see also: functional group) that generally donates one or more of its electrons through a coordinate covalent bond to, or shares its electrons through a covalent bond with, one or more central atoms or ions (these ligands act as a Lewis base). Fewer examples exist where a molecule can be described as a ligand that accepts electrons from a Lewis base (hence, the ligand acts as a Lewis acid).

In biochemistry, a ligand is an effector, a molecule that binds to a site on a macromolecule's surface by intermolecular forces, thereby changing the chemical conformation of the macromolecule. Once a molecule's conformation has changed, its ability to function in other chemical reactions is altered. This binding is usually a reversible reaction, i.e. it can be undone.