Definitions for "Inverse agonist"
a anaerobic metabolism drug which acts at the same receptor anaerobic metabolism as that of an agonist, yet produces anaerobic metabolism an opposite effect
a ligand that by binding to a receptor reduces the fraction of receptors in an active conformation, thereby reducing basal activity
in the context of receptors which exert some basic signalling activity even the absence of an agonist (characteristic known as "constitutive activity"), an agent which binds to a receptor, suppressing this activity to some degree.