Definitions for "Alagille Syndrome"
Keywords:  bile, ducts, buildup, liver, inherited
(al-uh-GEEL sin-drohm) A condition of babies in their first year. The bile ducts in the liver disappear, and the bile ducts outside the liver get very narrow. May lead to a buildup of bile in the liver and damage to liver cells and other organs.
An inherited disorder most commonly seen in children. The syndrome causes loss of the bile ducts within the liver and narrowing of the bile ducts outside the liver during the first years of life.
A dominantly inherited disorder that is characterized primarily by a scarcity of bile ducts in the liver. Other features include heart, eye, kidney and skeletal abnormalities, as well as defects in the central nervous system.