Definitions for "Systemic lupus erythematosus"
An autoimmune disease in which many different organs inside the body as well as the skin can be damaged. Sun sensitivity (photosensitivity) is a common feature of systemic lupus.
Lupus is believed to be an autoimmune disease. The cause of lupus has yet to be determined. The immune system is your body's defense mechanism against foreign particles called antigens. Sometimes the immune system loses the ability to distinguish between its own body components and antigens. Instead of fighting antigens, the antibodies mistakenly fight the body's own cells. This is referred to as an autoimmune response (auto means self) and the body mistakenly makes autoantibodies. A systemic disease is one in which several different parts of the body may be affected. In systemic lupus, these include the skin, kidneys, nervous system, lungs, heart and/ or blood-forming organs.
a disease of the immune system that causes inflammation of connective tissue in many areas of the body, including the skin, lungs, heart, joints, and kidneys