Definitions for "Polycythemia Vera"
The Condition"...As the disorder progresses, the liver and spleen may enlarge, causing a dull, intermittent ache in the abdomen..."
A neoplastic transformation of all blood cell lines (erythrocyte, leukocyte, and platelet) associated with increased numbers of cells in the peripheral blood. Contrast with secondary erythrocytosis as seen in cyanotic heart disease. see also erythrocytosis.
A clonal disease characterized by the over-production of blood cells by a mutant multipotential hematopoietic stem cell in the marrow. The hallmark of the disease is an increased number of red cells. The number of white blood cells and platelets are also usually increased. The accumulation of red cells is progressive and usually requires treatment at the time of diagnosis. The increase in white cells is ysually slight but the increase in platelets may become troublesome and require treatment as well.