cyclized form of the nucleotide adenosine monophosphate that serves as a signaling molecule in many kinds of cells. In bacteria, cAMP is low in cells that are grown in media containing glucose but cAMP levels increase in cells starved for glucose. As cAMP levels rise, cAMP binds to CRP, and the complex can bind to the promoters of genes such as the lac operon, that are involved in catabolism of nutrients other than glucose.
A modified version of AMP in which an intramolecular phosphodiester bond links the 5' and 3' carbons.
Cyclic 3'-5' adenosine monophosphate - a nucleotide derived from ATP thorough the action of adenylyl cyclase. Used as a second messenger by a number of hormones.
cAMP) second messenger, produced in response to hormonal stimulation of certain G protein coupled receptors, that activates cAMP-dependent protein kinases. ( Figure 20-4)
An intracellular second messenger synthesized by the enzyme adenylyl cyclase from ATP.
Nucleotide that is generated from ATP in response to hormonal stimulation of cell-surface receptors. cAMP acts as a signaling molecule by activating A-kinase; it is hydrolyzed to AMP by a phosphodiesterase.
The intracellular signalling molecule cyclic adenosine monophosphate, which is generated by the hydrolysis of adenosine triphosphate (ATP) by G-protein-dependent adenylyl cyclase.
A second messenger that begins the biological response initiated by a hormone. Cyclic AMP is derived from ATP. Many endocrine hormones use cyclic AMP as their second messenger.
A small, ring shaped molecule that acts as achemical signal in slime molds, as an intracellular second messenger in vertebrate endocrine systems, and as a regulator of the lac operon.