Group of symptoms that occur when a tumor called a gastrinoma forms in the pancreas. The tumor releases large amounts of the hormone gastrin, which causes too much acid in the duodenum, resulting in ulcers, bleeding, and perforation.
A disorder in which tumors of the pancreatic islet cells produce large amounts of gastrin (a hormone), leading to excess acid in the stomach and, possibly, a peptic ulcer (ulcer of the stomach or the upper part of the small intestine).
Zollinger-Ellison syndrome is a disorder where increased levels of the hormone gastrin are produced, causing the stomach to produce excess hydrochloric acid. Often, the cause is a tumour of the pancreas producing the hormone gastrin. Gastrin then causes an excessive production of acid which can lead to peptic ulcers.