Towards the Internet away from the school. For example (relative to your school), the BrightSparks network is upstream of VicOne, which in turn is upstream of your school network.
in Internet access, is traffic originating at the customer end and travelling toward the service provider, possibly for transit to other points on the Internet.
Upstream refers to a relative position in DNA or RNA. Each strand of DNA or RNA has a 5' end and a 3' end, so named for the carbons on the deoxyribose ring. Relative to the position on the strand, upstream is the region towards the 5' end of the strand.