A severe chromosomal disorder caused by the presence of an extra #18 chromosome. Physical findings may include: characteristic face and hand positioning, short sternum, small pelvis with limited hip mobility, rocker-bottom feet, congenital heart defects, hypertonia, and growth and mental retardation. If liveborn, death usually occurs by 6 months, although some children may survive for years.
or Edward's syndrome caused by meiotic nondisjunction; major clinical findings include mental retardation and periarticular limitation of motion of distal interphalangeal joints.
Edward's syndrome or trisomy 18 is a chromosomal abnormality, which is more severe and less common than Down's syndrome. Symptoms include severe learning disabilities and often numerous defects, such as cleft lip and palate, club foot, and malformation of internal organs.
A chromosomal (genetic) disorder where there is an extra copy of Chromosome 18 leading to a series of birth defects. For more information see the Factsheet on Trisomy 18.
A congenital condition causing severe mental retardation and often death before age 1. Caused by an extra chromosome number 18.
a genetic disorder in which an individual has an extra 18th chromosome, characterized by mental retardation, abnormal skull shape, malformed ears, and cardiac defects; the condition is usually fatal within several weeks or months of birth
A severe birth defect caused by a chromosomal abnormality. Children with the disorder have small eyes,abnormally formed ears, and heart problems, are severely mentally retarded, and rarely live past one year.
A congenital disease caused by an extra copy of chromosome 18. Infants with trisomy 18 rarely survive past six months of age due to multiple birth defects.
the presence of three #18 chromosomes, also known as Edwards syndrome.
Rare chromosomal disorder in which symptoms vary across individuals. These symptoms may include malformations of the head and face, small jaw, malformed low-set ears, widely spaced eyes, drooping of upper eyelids, malformations of the hands and feet inclu