Tris is an abbreviation of the trivial name (trishydroxymethylaminomethane) for 2-amino-2-hydroxymethyl-1,3-propanediol. It is widely used as a component of buffer solutions, such as in TAE and TBE buffers used in biochemistry, with an effective p H range between 6.5 and 9.7. Tris has labile protons with a p Ka of 8.30 (at 20 °C; this declines approximately 0.03 units per degree Celsius rise in temperature).