Change from a purine to a pyrimidine (adenine to thymine, for example) or from a pyrimidine to a purine. Compare transition.

The substitution of a purine for a pyrimidine, or a pyrimidine for a purine.

This is a substitution of a purine for a pyrimidine or vice versa.

Exchange of purine with pyrimidine (or vice versa)

A type of nucleotide-pair substitution in which a purine replaces a pyrimidine or vice versa for example, GC TA.

In molecular biology, Transversion refers to the substitution of a purine for a pyrimidine or vice versa. It can only be reverted by a spontaneous reversion. Because this type of mutation changes the chemical structure dramatically, the consequences of this change tend to be more severe and less common than that of Transitions.