The use of somatic cell nuclear transfer to produce embryonic stem cells suitable for differentiation into tissues that are a perfect match to treat disease in the person who provided the cell nucleus used. Ethically controversial.
Medical and scientific applications of cloning technology that do not result in the production of genetically identical fetuses or babies. For more information see Therapeutic cloning for tissue repair (Australian Academy of Science).
nuclear transplantation of a patient's own cells to make an oocyte from which immune-compatible cells (especially stem cells) can be derived for transplant
Generally referred to as somatic cell nuclear transfer technology. It involves replacing the nucleus of an egg cell with the nucleus from a cell from a patient's body and allowing it to develop to form a blastocyst. The embryonic stem cells from the inner cell mass are then harvested and used to establish a cell line that has the same genetic makeup of the patient. These cells can then be directed to develop into the tissue needed for transplant.
The cloning of an embryo for the purpose of deriving stem cells for use in research and treatment of disease.
somatic cell nuclear transfer (SCNT) where the resulting cloned embryo is allowed to develop to the blastocyst stage or farther, and then destroyed for stem cells or other tissue.
Creating a cloned embryo and growth to the blastocyst stage, for the purpose of harvesting embryonic stem cells.
Creating a cloned human embryo for experimental purposes, including destroying it to harvest embryonic stem cells or tissues.
medical and scientific applications of cloning technology which do not result in the production of genetically identical fetuses or babies. These techniques may be undertaken to advance fundamental research and therefore not all such applications will lead to immediate therapeutic utility.
When cells are copied with the intention of creating matching cells. Also see definition for nuclear transfer.
Using somatic cell nuclear transfer to isolate embryonic stem cells, these cells can then be instructed to form particular cell types, for example heart muscle. If the stem cells are placed back into the individual who gave the DNA for the somatic cell nuclear transfer, these cells are genetically identical and thus immunocompatible (they will not be rejected).
A term used to describe the process of generating a human embryo via somatic cell nuclear transfer for the specific purpose of obtaining stem cells for use in regenerative medicine.
