A spontaneous mutation is a mutation that is not inherited. Instead, the mutation occurs in the affected individual during the earliest stages of development, at or just after fertilization. Also known as a new, or sporadic, mutation.
although Marfan Syndrome is passed from parent to child by autosomal dominant inheritance, it can also occur spontaneously (without apparent reason) in an individual. These patients are usually seriously affected and can pass the disorder to their children. Back to the top