Definitions for "Shotgun sequencing"
An approach used to decode an organism's genome by shredding it into smaller fragments of DNA which can be sequenced individually.
DNA sequencing method. Breaks chromosomal DNA into small overlapping fragments which are individually sequenced, the entire sequence is then "reconstructed" by linking overlapped sequences together. This method has been used for whole genome sequencing. (More? Molecular Notes)
sequencing of randomly fragmented portions (~50Kb) of the genome.