moving a cell nucleus and its genetic material from one cell to another
Somatic cell nuclear transfer. also known as cloning, a procedure where the nucleus of an egg is removed and the nucleus of a somatic cell is placed in the egg. The egg is then "shocked" and begins to grow as if it were fertilized. The resulting embryo is a genetic clone of the donor of the somatic cell. Often called therapeutic cloning.
Somatic Cell Nuclear Transfer. See definition for nuclear transfer.
Somatic cell nuclear transfer. the replacement of genetic material (nuclear DNA) in an unfertilized egg with genetic material from an adult somatic cell (e.g., skin cell). Stem cells that genetically match the adult somatic cell donor can be derived. See graphic.
Somatic cell nuclear transfer. A method of cloning: transfer of the nucleus from a donor somatic cell into an enucleated egg to produce a cloned embryo.
Somatic cell nuclear transfer. A cloning technique where the nucleus from an unfertilized egg is removed and replaced with the nucleus from a somatic cell. The resulting egg will carry the full complement of genetic material of the host organism. This is how Dolly the cloned sheep was produced; she was genetically identical to her "mother". This technique can be used both for reproductive cloning and therapeutic cloning.
Somatic Cell Nuclear Transfer. Sometimes known as therapeutic cloning. A process by which a nucleus from a single cell (for example a skin cell) is transferred into an unfertilized egg, from which the nucleus (the genetic contents) have been removed. The resulting reconstructed embryo is which is then allowed to develop to the blastocyst stage. Embryonic stem cells derived from this blastocyst are genetically identical to the donor of the original nucleus.
Somatic cell nuclear transfer. Technique by which a somatic cell nucleus is transplanted into an ovum whose own nucleus has been removed (enucleated). Process also referred to as nuclear transfer or transplantation.
somatic cell nuclear transfer. In SCNT, a nucleus from a patient's body cell, such as a skin cell, is introduced into an unfertilized egg from which the original genetic material has been removed. The egg is then used to produce a blastocyst whose stem cells could be used to create tissue that would be compatible with that of the patient. This is called therapeutic cloning. Its advocates say the process does not result in the creation--or destruction--of human life because the egg is never fertilized or implanted in a uterus, as it would be in reproductive cloning.