Cancer of the retina (internal layer of the eye). Found almost exclusively in infants and young children.
disease marked by tumors of the retina of the eye that usually strikes children.Both familial and sporadic forms are known. Tumors cells typically have mutations in the tumor suppressor gene RB. The RB gene product may suppress cell division by binding to other proteins that regulate the cell cycle.
Hereditary, malignant intraocular tumor that develops from retinal cells. If untreated, numerous seedling nodules produce secondary tumors, gradually filling the eye and extending along the optic nerve and to the brain, ending in death. Most common childhood ocular malignancy. See Free Eye Tests.
An eye tumor that is an example of an inherited malignant tumor with a dominant autosomal gene inheritance pattern.
An eye cancer that most often occurs in children younger than 5 years. It occurs in hereditary and nonhereditary (sporadic) forms.
A rare cancer of the eye. This cancer can either be inherited or just develop spontaneously.
Rare, slow growing tumor that is located on the retina of the eye.
A cancer of the human retina. Predisposition to retinoblastoma is inherited as an autosomal dominant. A childhood cancer of retinoblast cells caused by the inactivation of an anti-oncogene.
malignant ocular tumor of retinal cells; usually occurs before the third year of life; composed of primitive small round retinal cells
A rare form of cancer which causes tumors to grow on the retina of children. In most cases, the tumors began developing before the child was born. RB can affect both eyes (bilateral RB) or it can affect only one eye (unilateral RB). RB is caused by a mutation in the developing retina cells of the child. This mutation can either have been inherited from either parent or it can be just a spontaneous mistake. RB is completely cured in 96% of the cases with modern medical care. While RB is a genetic disease, only about 5-8% of families have a positive family history. In most cases, the affected child is the first family member to have RB.
Tumor of childhood arising in the retina of the eye.
A hereditary, cancerous tumor of the retina affecting infants and children.
embryonic tumor of the retina in young children associated with deletion of the long arm of chromosome 13 containing the retinoblastoma gene (RB 1); the most common intraocular, potentially fatal pediatric tumor that affects about one in 25,000 live births.
Ret-in-OH-blast-OH-mah] A cancerous tumor of the retina which typically affects children under 5 years of age.
A tumor of the retina of the eye, often evident in infancy.
A malignant tumor involving the retina, usually effecting children in the first three years of life. It can be hereditary.
The most common cancer in the eye occurring in early childhood. A parent or doctor may first suspect a problem by detecting whiteness in the normally dark pupil. Occasionally it leads to a wandering eye (strabismus). It does not spread from one eye to the other but about 25% have a tumor in each eye. Immediate medical treatment is necessary. Sometimes the eye(s) must be removed to prevent spreading of the tumor into the brain.
Highly lethal tumor that tends to develop in the retinas of infants and young children. Can be hereditary and also spontaneous. Early treatment can be a life saver.
A malignant cancerous tumor of the retina. Go to Top
eye cancer caused by the loss of both copies of the tumor suppressor gene RB.
Cancer of the eye that mostly affects children under five. Occurs as inherited and non-inherited ( sporadic) forms.
Malignant tumor of the retina, usually arising in the inner nuclear layer of the neural retina. Retinoblastoma is unusual in being caused by an autosomal dominant mutation in some cases (about 6%), in which case it may be bilateral. The gene product of the retinoblastoma gene is a tumor suppressor that interacts with transcription factors such as E2F to block transcription of growth regulating genes. The Rb gene plays a role in normal development, not just that of the retina.
cancer of the retina (back of the eye).
A malignant tumor of the retina. Retinoblastoma is caused by a mutation in a gene and can affect the entire body, not just the retina of the eye. The product of the retinoblastoma gene is a tumor suppressor that works with transcription proteins such as E2F to block the formation of growth regulating genes. It is also called the Rb gene.
A malignant tumor that forms on the retina. Retinoblastoma most often affects children under the age of 5. It can occur in one or both eyes.
A childhood cancer of the human retina.
Congenital tumor inside the eye
Retinoblastoma is a disease in which cancer (malignant) cells are found in the retina. The retina is a thin membrane on the back of the inside of the eye. The retina works like a camera, making a picture of what you see. Retinoblastoma is not very common and occurs mostly in young children.
An eye cancer that most often occurs in children under the age of 5. It occurs in hereditary and nonhereditary (sporadic) forms.
an eye cancer caused by the loss of a pair of tumor-suppressor genes; the inherited form typically appears in childhood, since one gene is missing from the time of birth.
A tumor of the retina, occurring in children.
Retinoblastoma is a cancer of the retina. Development of this tumor is initiated by mutations that inactivate both copies of the RB1-gene, which codes for the Rb-1 protein. It occurs mostly in children before the age 5 years and accounts for about 3% of the cancers occurring in children younger than 15 years.