Definitions for "Retinoblastoma"
Cancer of the retina (internal layer of the eye). Found almost exclusively in infants and young children.
disease marked by tumors of the retina of the eye that usually strikes children.Both familial and sporadic forms are known. Tumors cells typically have mutations in the tumor suppressor gene RB. The RB gene product may suppress cell division by binding to other proteins that regulate the cell cycle.
Hereditary, malignant intraocular tumor that develops from retinal cells. If untreated, numerous seedling nodules produce secondary tumors, gradually filling the eye and extending along the optic nerve and to the brain, ending in death. Most common childhood ocular malignancy. See Free Eye Tests.