A group of glycoproteins that contain a core protein to which is attached one or more glycosaminoglycans. They are found in nearly all extracellular matrices, and some are attached to the plasma membrane.
Proteoglycan consists of glycosaminoglycan chains covalently bound to a core protein and found in ground substance.
Any of a class of glycoproteins of high molecular weight that are found especially in the extracellular matrix of connective tissue.
a glycoprotein whose carbohydrate units are glycosaminoglycans
important component of the matrix in hyaline cartilage[ back
A molecule that contains both protein and glycosaminoglycans, which are a type of polysaccharide. Proteoglycans are found in cartilage and other connective tissues.
large compound comprised of protein and polysaccharide units known as glycosaminoglycans (GAGs). GAGs are polymers of sugars and amino sugars, such as glucosamine or galactosamine. Proteoglycans are integral components of structural tissues such as bone and cartilage.
Proteoglycans represent a special class of glycoproteins that are heavily glycosylated. They consist of a core protein with one or more covalently attached glycosaminoglycan chain(s). These glycosaminoglycan (GAG) chains are long, linear carbohydrate polymers that are negatively charged under physiological conditions, due to the occurrence of sulphate and uronic acid groups.
