A protease is an enzyme that cleaves proteins at specific recognition sites determined by amino acid type or sequence, reducing a protein to shorter peptides or amino acids. Proteases are found throughout the body, and in the laboratory, are essential tools in preparing proteins for characterization via biochemical techniques.
An enzyme which cuts ribbons of newly fabricated HIV in order to make viral particles. To make new copies of itself inside infected cells, HIV depends on several enzymes. All of these enzymes have specific jobs in the HIV replication process. Protease is one of HIV's enzymes, and it is required to continue the process of HIV infection. Its job comes near the end of HIV replication. By then, HIV has already entered the cell's nucleus and has made long chains of proteins and enzymes that will form many new copies of HIV. But before they can produce working viral particles, the long chains have to be cut into smaller pieces. The HIV protease enzyme is like a "chemical scissors" because it cuts the long chain into shorter pieces.5
an enzyme that cleaves proteins. HIV protease cleaves the large precursor proteins produced from viral RNA into the component parts (e.g., enzymes and structural proteins) that are then assembled into new viral particles. Protease is essential for the production of infectious new virions.
Enzymes that are involved in the breakdown of proteins. They are most widely used enzyme in detergents; it removes protein stains from egg, grass, blood, and sweat. Also used to treat wool and raw silk.
A substance in the blood that breaks down proteins. Drugs that inhibit protease may stop HIV from breaking down the proteins it needs to grow. Protease inhibitor trials involving PWAs are showing promise and the first drugs are being introduced.
Protease enzymes digests protein. Taking protease enzymes with meals spares the natural pool of protease enzymes circulating in the blood so that they can continue to breakdown and destroy unwanted fungi, bacteria and viruses in the bloodstream.
An enzyme that triggers the breakdown of proteins. HIV's protease enzyme breaks apart long strands of viral protein into the separate proteins making up viral core. The enzyme acts as new virus particles are budding off a cell membrane.
Proteases (proteinases, peptidases, or proteolytic enzymes) are enzymes that break peptide bonds between amino acids of proteins. The process is called peptide cleavage, a common mechanism of activation or inactivation of enzymes, especially those involved in blood coagulation or digestion. They use a molecule of water for this and are thus classified as hydrolases.