Not having sex (abstinence) is the best way to prevent STDs. Other ways include: Have sex with only one uninfected person who only has sex with you. Limit the number of your sex partners to reduce exposure to all STDs. Use latex condoms consistently and correctly for all types of sexual penetration (oral, vaginal, anal). Use spermicides (foams, jellies, creams or suppositories) with condoms for additional protection during vaginal intercourse. Spermicides are not recommended for oral sex or anal sex. Talk with your partner(s). Careful consideration and open communication between partners may protect all partners involved from infection. Have regular check-ups, at least once a year, if you are sexually active. Talk honestly to your provider about your sexual practices and ask about STD tests. If you have an STD, don't have sex (oral, vaginal, anal) until all partners have been treated.