a genetically altered mouse that has a tendency to develop cancer. It was created by modifying the regulatory mechanism of the myc gene and injecting the gene into a mouse embryo. OncoMouse® is a trademark of DuPont MPF

The Oncomouse or Harvard mouse is a type of laboratory mouse that has been genetically modified using modifications designed by Harvard University and DuPont to carry a specific gene called an activated oncogene. The activated oncogene significantly increases the mouse’s susceptibility to cancer, and thus makes the mouse suitable for cancer research.