A synthetic amino acid (C5H9NO4) that binds selectively to a subset of glutamate receptors on neurons where the binding of glutamate results in the opening of calcium channels. Also called N-methyl-D-aspartate.
N-methyl, D-aspartate - a subtype of glutamate receptor.
The N-methyl-D-aspartate (NMDA) receptors in the dorsal horn of the spinal cord are an important part of the pain transmission pathway, and are implicated in the development of central sensitisation. Blocking the pathway at this point is possible with NMDA antagonist drugs such as ketamine.
a neurotransmitter that has some regulatory control over dopamine production
N-methyl-D-aspartate. A hallucinogen
See N-methyl D-aspartate receptor.
NMDA (N-methyl-D-aspartic acid) is an amino acid derivative acting as a specific agonist at the NMDA receptor, and therefore mimics the action of the neurotransmitter glutamate on that receptor. In contrast to glutamate, NMDA binds to and regulates the above receptor only, but not other glutamate receptors.