Definitions for "Neurofibrillary tangle"
an intraneuronal mass composed of normal intermediate filaments and paired helical filaments having unusual properties, which twist and form tangles
A pathological feature found in the brains of patients with Alzheimer's disease. Neurofibrillary tangles are abnormal intracellular accumulations of a microtubule-associated protein called tau.
Protein that accumulates in the brain of Alzheimerâ€(tm)s disease patients.