a substance that maintains the health of nerve cells. NGF also promotes the growth of axons and dendrites, the parts of the nerve cell that are essential to its ability to communicate with other nerve cells.
a naturally produced substance that has many roles in the maintenance of nerves and nerve cells, especially sensory ones. Synthetic, RECOMBINANT NGF is a proposed therapy for HIV- and drug-associated NEUROPATHIES.
Nerve growth factor (NGF), the prototypical growth factor, is a protein secreted by a neuron's target. NGF is critical for the survival and maintenance of sympathetic and sensory neurons. NGF is released from the target cells, binds to and activates its high affinity receptor (Trk A), and is internalized into the responsive neuron.