Definitions for "Megaloblastic Anemia / Pernicious Anemia"
The Condition"...Megaloblastic anemias are usually caused by a deficiency or defective absorption of either vitamin B12 (cobalamin) or folic acid..." Recommendation Test for B12 Levels"...When testing facilities are not available or cannot be afforded, intramuscular or sublingual B12, with or without folic acid, can be used to see if symptoms improve..." Recommendation Rest"A person with folic acid deficiency anemia should rest as often as necessary until restored energy levels make it possible to resume regular activities..." Recommendation Test Folic Acid Levels"Prevention of folic acid deficiency anemia involves eating raw or lightly-cooked vegetables every day..."
The Condition"...Tingling of the hands and feet, as well as the onset of spastic movements, may indicate that the nervous system has been affected..." Recommendation Test Folic Acid Levels"...Unless the B12 deficiency is corrected, permanent nervous system damage may result..."
The Condition"...The result is vitamin B12 deficiency, which gradually affects sensory and motor nerves, causing neurological, gastrointestinal and cardiovascular problems..."
The Condition"...Weight loss and lack of appetite (anorexia) may also occur, as well as jaundice, confusion and depression..."
The Condition"...Enlargement of liver and spleen (hepatosplenomegaly) may also occur, accompanied by yellow discoloration of the skin (jaundice) or pallor..."