a genetic predisposition to cancer, due to the presence of a genetic mutation in the p53, suppressor gene.
an inherited family trait carrying an increased risk of cancer during childhood and early adulthood.
A rare, inherited familial cancer syndrome characterized by tumors at multiple sites. A mutation of the p53 tumor suppressor gene predisposes family members who inherit it to develop multiple cancers.
A family cancer syndrome. WWW Resources for Li-Fraumeni Syndrome / TP53
A rare familial syndrome characterized by increased suceptibility to developing early breast cancers and soft tissue sarcomas.Caused by an alteration in the p53 tumor suppressor gene.
a family predisposition to multiple cancers, caused by a mutation in the p53 tumor suppressor gene.
A syndrome is a collection of symptoms. Individuals with this syndrome have an increased risk of developing a number of different cancers.
A rare, inherited predisposition to multiple cancers, caused by an alteration in the p53 tumor suppressor gene.
Li-Fraumeni syndrome is a rare autosomal dominant hereditary disorder. It is named after Frederick Pei Li and Joseph F. Fraumeni, American physicians who originally described the syndrome.
