A technique where a denatured (single-stranded) nucleotide chain (DNA or RNA) is allowed to pair with another single-stranded nucleotide chain. Hybridization will only occur if the two sequences are sufficiently related for a substantial number of hydrogen bonds to form between their complementary bases.
1. Joining of two complementary strands of DNA, or of DNA and RNA, to form a double stranded molecule. 2. Process of sexual exchange between two plants to produce hybrid plants.
Association of two complementary nucleic acid strands to form double-stranded molecules, which can contain two DNA strands, two RNA strands, or one DNA and one RNA strand. Used experimentally in various ways to detect specific DNA or RNA sequences.