Definitions for "HLA-B27"
A gene that has been linked to ankylosing spondylitis. People carrying this gene are more likely to develop spondylitis. When HLA-B27 is present on blood cells, it indicates susceptibility to a group of diseases called seronegative spondyloarthropathies.
An HLA class I molecule that has been assigned the number 27; its gene is present at the B locus. There are quite a few HLA antigens that confer susceptibility to certain diseases: HLA-B27 to AS, and HLA-DR4 to rheumatoid arthritis, for example.
A gene that confers susceptibility to certain diseases such as ankylosing spondylitis.