Until the specific actions of supplemental glucosamine are determined, the mechanism of action in relieving arthritic pain and in repair of cartilage is a matter of speculation. However, we do know a great deal about the biochemistry of the molecules in which glucosamine is found. Biochemically, glucosamine is involved in glycoprotein metabolism. Glycoproteins, known as proteoglycans, form the ground substance in the extra-cellular matrix of connective tissue. Proteoglycans are polyanionic substances of high-molecular weight and contain many different types of heteropolysaccharide side-chains covalently linked to a polypeptide-chain backbone. These polysaccharides make up to 95% of the proteoglycan structure. In fact, chemically, proteoglycans resemble polysaccharides more than they do proteins.
Glucosamine is a compound naturally found in the joints of the body. Helps heal, relieve pain, reduce inflammation and improve joint damage.
Glucosamine helps maintain joint function and stimulate joint repair. It is a component of many tissues and structures of the body, including the bones, cartilage, eyes, heart, ligaments, nails, skin, and tendons.