(fa-MIL-yul pah-li-PO-sis) An inherited condition in which numerous polyps (tissue masses) develop on the inside walls of the colon and rectum. This condition increases a person's risk of developing colorectal cancer.
asyndrome in which a gene mutation that influences the development of colon, rectal, and other cancers is inherited. People with FAP usually have hundreds, and sometimes thousands of pre-cancerous polyps, or growths developing at a very early age. FAP is defined as the presence of more than 100 benign (adenomatous) polyps in the large intestine at one examination. Some people with FAP with a mild version of the disease have less than 100 adenomas; in these individuals the diagnosis is made by family history, or by finding the mutation during genetic testing.
(FAP). The development of numerous adomatous polyps in the colon that might progress to carcinomas.
(fa- mil-e-uhl ad-ehn- NO-mah-tus pa-lee-po-sis): an inherited condition that is a risk factor for developing colorectal cancer at a young age. People with this syndrome develop polyps in the colon and rectum. Usually one or more of these polyps becomes cancerous if preventive surgery is not done. This is due to changes in the APC gene. See also APC gene.
FAP is a condition in which the tendency to develop polyps is inherited. People with this condition generally develop hundreds to thousands of polyps throughout the colon at a young age, usually as teenager or a young adult.
(fa-mil-e-uhl ad-ehn-NO-mah-tus poly-po-sis) : an hereditary condition that is a risk factor for colorectal cancer. People with this syndrome develop polyps in the colon and rectum. Often these polyps become cancerous. Abbreviated FAP.
A rare genetic disorder of the intestines characterized by "carpet-like" growths of polyps that develop along the inner walls of the colon. These areas of abnormal growth typically develop at a relatively young age.
(fa-MEEL-ee-ul a-deh-NO-meh-tes pah-luh-PO-sis) ( listen) Genetic disease with numerous precancerous polyps in the colon and rectum. Also called familial polyposis.
People who have inherited the FAP syndrome usually develop up to thousands of colon polyps at a young age, as early as their teens; the polyps are benign but some become cancerous over time, and many FAP patients develop colon cancer before they are 40.
A hereditary condition that is a risk factor for colorectal cancer. People with this syndrome typically develop hundreds of polyps in the colon and rectum at an early age. Usually 1 or more of these polyps becomes cancerous if preventive surgery is not done.
an often hereditary gene mutation that has been found to determine a person's predisposition to colon cancer.
(FAP) or Gardner Syndrome. Characterized by the combination of polyps of the colon, extrabowel tumors and an abnormality of the retina of the eye. The disease is caused by a mutation in a gene and persons with the disease have a 50% chance of passing it to each of their children.
Abbreviated FAP. A syndrome characterized by the formation of thousands of polyps in the colon and rectum with colorectal cancer the inevitable consequence. Polyps can also occur in the stomach, duodenum and the terminal ileum . See the entire definition of Familial adenomatous polyposis
A rare hereditary disorder that runs in families. It is a condition in which large numbers of precancerous polyp growths are present in the colon (large bowel).
An inherited disorder of the gastrointestinal tract in which there are hundreds to thousands of precancerous polyps, usually caused by an inherited mutated copy of the Apc gene.
A hereditary condition in which members of the same family develop intestinal polyps. Also called Gardner's syndrome, it is considered a risk factor for colorectal cancer.
A rare disease that causes lots of benign polyps (small growths that are not cancerous) to grow in the bowel. People with FAP have an increased risk of getting bowel cancer.
An autosomal dominantly inherited predisposition to multiple adenomatous polyps of the colon and a risk for colorectal cancer that approaches 100% by age 60. The germ-line mutation for this disease is the APC gene, which stands for adenomatous polyposis coli. Other cancers, including papillary thyroid carcinoma, periampullary carcinoma, gastric cancer (particularly in FAP patients in Japan), small bowel cancer, pancreatic cancer, sarcomas and brain tumors, as well as desmoid tumors (which are not cancer) complicate this disease.
FAP. An inherited condition in which numerous polyps (growths that protrude from mucous membranes) form on the inside walls of the colon and rectum. It increases the risk for colorectal cancer. Also called familial polyposis.
a hereditary syndrome characterized by the formation of many polyps in the colon and rectum, some of which ultimately develop into colorectal cancer.
growth of multiple precancerous polyps over the mucosa of the colon and occurring in several members of the same family. A dominantly inherited disorder characterised by the presence of a Germline mutation in the gene APC, found on the long arm of chromosome 5.
A dominantly inherited cancer-predisposing syndrome characterized by the presence of a large number of polyps of the large bowel with a high risk of developing malignant changes.
an inherited condition in which hundreds of potentially cancerous polyps develop in the colon and rectum.
Familial adenomatous polyposis (FAP) is an inherited condition in which numerous polyps form mainly in the epithelium of the large intestine. While these polyps start out benign, malignant transformation into colon cancer occurs 100% of the time when not treated.