An enzyme that breaks the internal backbone in a DNA molecule.
A nuclease that cleaves nucleic acids at specific internal sites.
a nuclease that cleaves nucleic acids at interior bonds and so produces fragments of various sizes
an enzyme that can cleave the phosphodiester bonds of a nucleic acid at an internal site (as opposed to cleavage by an exonuclease , which can only remove nucleotides from one of the ends of a nucleic acid)
an enzyme that cuts duplex DNA in the middle, not at an end (for exonuclease)
A restriction enzyme that breaks up nucleic acid molecules at specific sites along their length. Such enzymes are naturally produced by microorganisms as a defense against foreign nucleic acids.
An enzyme that recognizes and cleaves DNA at specific sequences. Also called restriction enzymes, they are useful to scientists for analyzing gene structure and mutations.
An enzyme that cuts a single strand of DNA at a specific site. Some DNA repair enzymes are endonucleases.
An enzyme that cleaves single- or double-stranded DNA at interior positions. Endonuclease activity may be specific (e.g., restriction enzymes) or nonspecific (e.g., nickases).
An enzyme that breaks nucleic acids at specific interior bonding sites, thus producing nucleic acid fragments of various lengths. Cf. Exonuclease.
Enzymes that recognise and dissect a specific base order in a DNA sequence.
An enzyme that hydrolyzes nucleic acids. In contrast to exonucleases that are able to hydrolyze only the first or last nucleotide in a strand, endonucleases cleave a strand internally.
A nuclease which cleaves phosphodiester bonds within a nucleic acid strand. ( 16)
An enzyme that cleaves its nucleic acid substrate at internal sites in the nucleotide sequence.
An enzyme that cleaves at internal locations within a nucleotide sequence. The enzyme's site of action is generally a sequence of 8 bases. For E. coli, treatment with a restriction endonuclease will lead to around 70 fragments. Cleavage of human DNA leads to around 50,000 fragments.
An enzyme that breaks phosphodiester bond within a nucleic acid molecule.
Endonucleases are enzymes that cleave the phosphodiester bond within a polynucleotide chain. Restriction endonucleases (Restriction Enzymes) cleave DNA at specific sites, and are divided into three categories, Type I, Type II, and Type III, according to their mechanism of action. These enzymes are often used in genetic engineering to make recombinant DNA for introduction into bacterial, plant, or animal cells.