epidermal growth factor receptor. (eh-peh-DER-mul growth FACK-ter reh-SEP-ter) Protein on the surface of some cells to which epidermal growth factor binds, which causes the cells to divide. EGFR is found at abnormally high levels on the surface of many types of cancer cells. Also called ErbB1 or HER1.
transmembrane receptor- tk - EGF-R homology - during oogenesis helps set up egg polarity, determines the identity of cells in the ectoderm; during larval stages participates in the development of the eye and wing.
Epidermal Growth Factor Receptors