Serious disruption of blood clotting mechanisms, resulting in hemorrhaging or internal bleeding. Condition is a complication of an underlying disorder.
A phenomenon which arises due to the depletion of clotting elements in the blood; caused by many disease processes; diffuse, severe hemorrhaging can occur; without treatment, it is often fatal.
A bleeding disorder characterized by the excessive utilization of blood-clotting factors, due to widespread clotting within blood vessels; the resultant hemorrhaging often represents a terminal event in a number of diseases.
A condition in which the clotting factors and platelets in the blood are consumed due to infections, acidosis, hypoxia or other injuries or diseases.
The activation of blood-clotting factors and platelets inside the blood vessels throughout the body. It may be triggered by infection, burns, snake bite, or other factors and may result in uncontrolled bleeding because of the depletion of these elements.
Disseminated intravascular coagulation (DIC), also called consumptive coagulopathy, is a pathological process in the body where the blood starts to coagulate throughout the whole body. This depletes the body of its platelets and coagulation factors, and there is a paradoxically increased risk of hemorrhage. It occurs in critically ill patients, especially those with Gram-negative sepsis (particularly meningococcal sepsis) and acute promyelocytic leukemia.