A laboratory procedure for reducing the numbers of a specific cell type within bone marrow donated for transplantation. One example is T lymphocyte depletion or removal. It is done to minimize immune reactivity of donor cells. This step may be used to decrease the likelihood or severity of graft versus host disease in circumstances in which donor-recipient matching is imperfect (particularly in relation to unrelated donor transplants).
Removal of free carriers in a semiconductor
a laboratory procedure for reducing the numbers of specific cell types within bone marrow donated for transplantation, for example the removal of some types of lymphocytes. This may be to avoid "mismatch" problems (particularly in relation to unrelated donor transplants) or to remove a sub-set of potentially leukaemic cells in an autograft.