To cause a protein to fold into a structure other than the native 3-D conformation; to convert double-stranded DNA to single-stranded DNA.
denatured; denaturation. A loss of chemical function, usually due to some heat or chemically-induced structural change. For example, heating a protein causes it to lose its three dimensional form and it no longer functions correctly.
modify (as a native protein) especially by heat, acid, alkali, or ultraviolet radiation so that all of the original properties are removed or diminished
to cause the structure of a protein to unfold, as with heat, alkali or acid, so that some of its original properties, especially its biological activity are diminished or eliminated
To change a protein from its native, functional structure to a different conformation, thereby also changing its function
to eliminate secondary and higher order structure from a molecule. In the SDS PAGE experiment, proteins are denatured using chemical compounds such as SDS (Sodium Dodecyl Sulfate) and 2-mercaptoethanol.
The loss or change of the native 3-dimensional structure of a biomolecule.