Condition resulting from continuous high levels of glucocorticoids, either as a result of a neoplasm of the adrenal cortex or the pituitary, or continued administration of high levels of steroid drugs.
Cushing's Syndrome, first described by neurosurgeon Harvey Williams Cushing, is the collection of symptoms and signs caused by an excess of cortisol, the primary stress hormone. Cushing's syndrome is an extremely complex hormonal condition involving many areas of the body. Symptoms include weakness, bruising, thinning of the skin, weight gain, hypertension, diabetes, osteoporosis, facial puffiness, and in women cessation of periods. One of the most common causes of Cushing's syndrome is the use of cortisol-like medications for the treatment of various diseases. All other cases of Cushing's syndrome are due to excess production of cortisol by the adrenal gland including 1) a benign or malignant growth within the adrenal gland, which produces cortisol, 2) an abnormal growth of the pituitary gland, which stimulates the adrenal gland, and 3) production within another part of the body (ectopic production) of a hormone that directly or indirectly drives the adrenal gland to make cortisol.
A condition characterized by an over production of adrenal gland secretions. The person will suffer from high blood pressure and water retention as well as a number of other symptoms. A concurrent elevation of adrenal androgens will suppress pituitary output of LH and FSH and result in low sperm production or ovulatory failure. A woman may also develop male secondary sex characteristics, including abnormal hair growth. Cushings Disease is another condition in which these same symptoms occur, but as the result of a pituitary tumor.
A rare disorder caused by too much cortisol (an adrenal gland hormone) in the system, causing body weight to increase while height remains constant. Symptoms may include bruising, thinning of the skin, softening of the bones, and weakening of the muscles. Cushing's Syndrome may be caused by an overactive pituitary gland, the presence of a tumor in the adrenal glands, or over-medication with cortisol pills used to treat asthma and other diseases. Treatment depends on the cause, but one option may be growth hormone therapy.
a condition in which an excess of corticosteroid hormones leads to symptoms such as rounded face, increased upper body fat, fragile skin, high blood sugar, high blood pressure, fatigue, and weakened bones.
Possible side effect of topical corticosteroids. Characterized by exaggerated roundness of the face, a fatty hump on the back, edema, striae on the trunk, wasting of the limbs, and obesity of the trunk.
A complex condition caused by an excess of the hormone, cortisol. Common signs and symptoms include thinning of the skin, weakness, weight gain (especially in the trunk), easy bruising, hypertension, glucose intolerance, osteoporosis, facial puffiness and, in women, irregular menstrual cycles.
Cushing's syndrome or hypercortisolism or hyperadrenocorticism is an endocrine disorder caused by excessive levels of the endogenous corticosteroid hormone cortisol. It may also be induced iatrogenically by treatment with exogenous corticosteroids for other medical conditions. It was discovered by American physician, surgeon and endocrinologist Harvey Cushing (1869-1939) and reported by him in 1932.