The precise shape of a protein or other macromolecule in three dimensions resulting from the spatial location of the atoms in the molecule. A small change in the conformations of some proteins affects their activity considerably.
A molecular geometry that differs from other geometries chiefly by rotation about single or triple bonds; distinct conformations (termed con formers) are associated with distinct potential wells. Typical biomolecules and products of organic synthesis can interconvert among many conformations; typical diamondoid structures are locked into a single potential well, and thus lack conformational flexibility.
Conformation refers to protein folding and the effects of three-dimensional structure on protein function. Events that affect protein conformation are the interactions of a protein with other proteins and post-translational modifications. Environment is crucial to proper protein folding and creation of a stable conformation. The cell often destroys proteins whose conformations are not stable. See also Denaturation, Disulfide Bond, Domain, Secondary Structure, Structural Biology, Tertiary Structure.
a trial event in which the terrier is judged on the degree in which various angles and parts of the body agree or harmonize with each other (based on a breed standard). In addition to conformation and movement, the dog is judged on temperament; as in all things having to do with Jack Russells, the best working dog is being sought. ( info)
the spatial arrangement of a molecule in space at any particular moment in time. [Most molecules can adopt an infinite number of conformations because of the possible rotation about single covalent bonds. Of these possibilities most compounds tend to spend most time in only one or a few conformational states, called the preferred conformations.
When you place a bet you will be asked to confirm the details. The bet will only be processed after this conformation has taken place. If there are any problems with the bet you will be notified at this point in time. The bet details can be viewed and printed from the Account History section found in Members Services.