Anticonvulsants are designed to reduce or inhibit the severity of epileptic or other convulsive seizures. They exert their anticonvulsive effect by stabilizing the cell membrane and decreasing intracellular sodium, thus reducing the excitability of the epileptogenic focus. Other anticonvulsants prevent the spread of excessive discharges in the cerebral motor areas and suppress dysrhythmias originating in the thalamus, frontal lobes and other brain areas.
or antiepileptic drugs, a class of therapeutic drugs that are used to prevent and minimize seizures by acting on either ion channels, active transport, or membrane stabilization. In embryology they are teratogenic and increase the occurance of neural tube defects (NTDs). (Drug examples: Carbamazepine, Clonazepam, Ethosuximide, Phenobarbital, Phenytoin, Primidone, Valproic Acid) (More? Neural Abnormalities | Neural Tube Defects | Drug Use)